Association of the serum uric acid to high-density lipoprotein cholesterol ratio with in-hospital mortality in patients with acute kidney injury: a retrospective cohort study - Scorecard - MDSpire
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Association of the serum uric acid to high-density lipoprotein cholesterol ratio with in-hospital mortality in patients with acute kidney injury: a retrospective cohort study
Clinical Scorecard: Link Between Serum Uric Acid to HDL Cholesterol Ratio and In-Hospital Mortality in Acute Kidney Injury Patients: A Retrospective Cohort Analysis
At a Glance
Category
Detail
Condition
Acute Kidney Injury (AKI)
Key Mechanisms
Uric acid to HDL cholesterol ratio (UHR) as a biomarker of metabolic inflammation and cardiovascular risk.
Target Population
Adults diagnosed with AKI according to KDIGO criteria.
Care Setting
Tertiary referral hospital
Key Highlights
UHR independently predicts in-hospital mortality in AKI patients.
Each unit increase in UHR is associated with a 55% higher hazard of in-hospital mortality.
Non-survivors had higher serum creatinine, blood urea nitrogen, and C-reactive protein levels.
Guideline-Based Recommendations
Diagnosis
AKI diagnosed according to KDIGO criteria.
Management
Further mechanistic studies are needed to understand the role of UHR in AKI.
Monitoring & Follow-up
Monitor UHR alongside other clinical parameters in AKI patients.
Risks
Higher UHR correlates with increased risk of in-hospital mortality.
Patient & Prescribing Data
500 adult AKI patients, with 65 non-survivors identified.
UHR may serve as a prognostic tool for risk stratification in AKI.
Clinical Best Practices
Utilize UHR for assessing mortality risk in AKI patients.
Consider age, serum creatinine, and CRP levels in conjunction with UHR.
