Utility of prenatal ultrasound in diagnosis and prognosis of aortic arch obstruction: a 10-year single-center retrospective study - Scorecard - MDSpire

Utility of prenatal ultrasound in diagnosis and prognosis of aortic arch obstruction: a 10-year single-center retrospective study

  • By

  • He Li

  • Jinwen Chen

  • Wen Ling

  • Qiumei Wu

  • Biying Huang

  • Guorong Lyu

  • Caihong Jiang

  • Zongjie Weng

  • July 3, 2026

  • 0 min

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Clinical Scorecard: Evaluating the Role of Prenatal Ultrasound in Identifying and Predicting Outcomes of Aortic Arch Obstruction: A Decade-Long Retrospective Analysis from a Single Center

At a Glance

CategoryDetail
ConditionAortic Arch Obstruction
Key MechanismsDifferentiation between interrupted aortic arch (IAA) and coarctation of the aorta (CoA) using prenatal echocardiography.
Target PopulationFetuses diagnosed with aortic arch obstruction.
Care SettingTertiary center prenatal care.

Key Highlights

  • Prenatal diagnostic accuracy for aortic arch obstruction was 90.28%.
  • IAA cases showed more severe hypoxia and cyanosis compared to CoA.
  • Intracardiac malformations occurred in 88.89% of cases.
  • IAA is associated with poorer early outcomes than CoA.
  • Close postnatal surveillance is required for CoA cases.

Guideline-Based Recommendations

Diagnosis

  • Utilize prenatal echocardiography to detect aortic arch obstruction.

Management

  • Maintain ductal patency with prostaglandin E1 in IAA cases.

Monitoring & Follow-up

  • Conduct timely neonatal cardiac management and assessment postnatally.

Risks

  • Higher prevalence of combined anomalies in IAA cases.

Patient & Prescribing Data

Fetuses diagnosed with IAA and CoA.

Surgical interventions significantly improve survival rates in infants with aortic arch obstruction.

Clinical Best Practices

  • Accurate prenatal differentiation between IAA and CoA is crucial for early risk stratification.
  • Implement advanced echocardiographic modalities to enhance diagnostic precision.

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