Iron deficiency in primary care patients with heart failure: a cross-sectional study of the heart failure in Southern Sweden (HISS) cohort - Scorecard - MDSpire

Iron deficiency in primary care patients with heart failure: a cross-sectional study of the heart failure in Southern Sweden (HISS) cohort

  • By

  • Fredrik Vinge

  • Oscar Braun

  • Moa Wolff

  • J. Gustav Smith

  • Kristina Sundquist

  • Veronica Milos Nymberg

  • July 3, 2026

  • 0 min

Share

Clinical Scorecard: Iron Deficiency Among Heart Failure Patients in Primary Care: A Cross-Sectional Analysis of the HISS Cohort in Southern Sweden

At a Glance

CategoryDetail
ConditionHeart Failure
Key MechanismsIron deficiency is a common comorbidity affecting symptom burden and exercise capacity.
Target PopulationAdult patients (≥ 18 years) with heart failure in primary care.
Care SettingPrimary care managed heart failure patients.

Key Highlights

  • Approximately 40% of heart failure patients have iron deficiency.
  • Iron deficiency prevalence increases with worsening NYHA class.
  • Intravenous iron is recommended for symptomatic heart failure with LVEF < 50% and iron deficiency.

Guideline-Based Recommendations

Diagnosis

  • Iron deficiency defined as ferritin < 100 µg/L or ferritin 100–299 µg/L with TSAT < 20%.

Management

  • Intravenous iron therapy is recommended to improve symptoms and reduce hospitalisation risk.

Monitoring & Follow-up

  • Monitor TSAT and ferritin levels to assess iron status.

Risks

  • Increased symptom burden and risk of hospitalisation associated with iron deficiency.

Patient & Prescribing Data

Patients with chronic heart failure managed in primary care.

Oral iron supplementation has not shown benefits in heart failure management.

Clinical Best Practices

  • Utilize TSAT-based definitions for iron deficiency assessment.
  • Early identification and treatment of iron deficiency may improve patient outcomes.

Related Resources & Content

Original Source(s)

Iron deficiency in primary care patients with heart failure: a cross-sectional study of the heart failure in Southern Sweden (HISS) cohort

  • by Fredrik Vinge, Oscar Braun, Moa Wolff, J. Gustav Smith, Kristina Sundquist, Veronica Milos Nymberg

  • July 3, 2026

Related Content

Cardiac Index Measured Using the Fick Principle Versus Thermodilution in Children Following Orthotopic Heart Transplantation

Hemodynamic Instability in Intubation May Be Predictable

Narrative review describes how physiologic stressors accumulate from induction through postintubation care and may contribute to cardiovascular deterioration during airway management.

ASE Plenary: Progress, Priorities, and What’s Next

Efforts to align, sustain, and engage drove a year of growth for ASE.