No association between alcohol consumption and hip osteoarthritis: a diverse national analysis of 87,585 adults from the “All of Us” research program - Scorecard - MDSpire
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No association between alcohol consumption and hip osteoarthritis: a diverse national analysis of 87,585 adults from the “All of Us” research program
Clinical Scorecard: Lack of Correlation Between Alcohol Intake and Hip Osteoarthritis: Insights from a Comprehensive National Study Involving 87,585 Participants in the 'All of Us' Initiative
At a Glance
Category
Detail
Condition
Hip Osteoarthritis
Key Mechanisms
Upregulated inflammatory processes and oxidative stress contribute to the disease course of OA.
Target Population
Individuals aged 18 years or older with hip osteoarthritis.
Care Setting
National precision medicine initiative utilizing diverse participant data.
Key Highlights
Study involved 87,585 participants, including 17,517 hip OA cases.
No significant association found between alcohol intake and hip OA.
Higher prevalence of diabetes, hypertension, hyperlipidemia, and nicotine dependence in hip OA cohort.
Guideline-Based Recommendations
Diagnosis
Diagnosis of hip OA based on EHR-documented cases using standardized SNOMED concepts.
Management
No established strategy to prevent or modify progression of hip OA.
Monitoring & Follow-up
Monitor demographic and clinical variables such as age, gender, and comorbidities.
Risks
Independent risk factors for hip OA include Asian race, diabetes, hypertension, hyperlipidemia, and nicotine dependence.
Patient & Prescribing Data
Participants with complete information on alcohol use frequency and hip OA status.
Alcohol consumption frequency did not show significant differences in odds of hip OA.
Clinical Best Practices
Utilize comprehensive datasets for understanding complex disease relationships.
Consider demographic and clinical covariates in OA research.
Postoperative rates of complex regional pain syndrome type 1 and pain and functional outcomes may improve among patients receiving prophylactic mecobalamin following foot and ankle surgery.
