The effect of rehabilitation training based on brain-computer interface on limb function in stroke patients: a systematic review and meta-analyses - Scorecard - MDSpire

The effect of rehabilitation training based on brain-computer interface on limb function in stroke patients: a systematic review and meta-analyses

  • By

  • Ziqiu Zheng

  • Changyue Zhang

  • Mengjiao Lv

  • Chunting Qian

  • Ge Gao

  • Saisai Wang

  • Rujing Zhu

  • Jing Yang

  • Chengwei Zhang

  • Haiyan Xu

  • July 1, 2026

  • 0 min

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Clinical Scorecard: Impact of Brain-Computer Interface-Based Rehabilitation on Limb Function Recovery in Stroke Patients: A Systematic Review and Meta-Analysis

At a Glance

CategoryDetail
ConditionStroke
Key MechanismsDisruption of neural pathways affecting motor function; BCI enhances neural plasticity and motor control.
Target PopulationPatients recovering from stroke with upper and lower limb dysfunction.
Care SettingRehabilitation training utilizing brain-computer interfaces.

Key Highlights

  • BCI significantly improved upper limb function (FMA-UE) with WMD = 3.50.
  • BCI significantly improved lower limb function (FMA-LE) with WMD = 2.59.
  • Twenty-seven RCTs included in the meta-analysis.
  • Traditional rehabilitation methods have limitations in efficacy and engagement.
  • BCIs provide real-time feedback and enhance neural plasticity.

Guideline-Based Recommendations

Diagnosis

  • Assess motor dysfunction in stroke patients using standardized scales.

Management

  • Incorporate BCI-based rehabilitation alongside traditional methods for limb recovery.

Monitoring & Follow-up

  • Evaluate progress using Fugl-Meyer Assessment scores.

Risks

  • Consider potential variability in individual responses to BCI interventions.

Patient & Prescribing Data

Stroke patients with varying degrees of limb dysfunction.

BCI-based training may enhance recovery outcomes compared to traditional rehabilitation alone.

Clinical Best Practices

  • Utilize non-invasive BCI systems for safety and effectiveness.
  • Integrate BCI with physical and occupational therapy for comprehensive rehabilitation.
  • Monitor patient engagement and adjust interventions based on real-time feedback.

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