Reflections from ASRS
Upfront: Monthly reflection by Editor in Chief Diana V. Do, MD.
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By
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Diana V. Do, MD
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September 1, 2025
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Clinical Scorecard: Reflections from ASRS
At a Glance
| Category | Detail |
|---|
| Condition | Retinal disorders including uveitis, ocular oncology, and pediatric retina |
| Key Mechanisms | Emerging treatments and technologies including IL-6 inhibitors and AI in ROP care |
| Target Population | Patients with vision-threatening retinal disorders |
| Care Setting | Ophthalmology clinics and surgical settings |
Key Highlights
- Importance of timely diagnosis and management of vasoproliferative tumors
- Advancements in AI for standardizing ROP diagnosis and monitoring
- Current investigations into IL-6 inhibitors for noninfectious uveitis
- Challenges and efficacy of the port delivery system (PDS) for ranibizumab
- Adaptation of PDS for novel therapeutics in retinal diseases
Guideline-Based Recommendations
Diagnosis
- Utilize advanced imaging and AI systems for accurate retinal diagnoses
- Timely diagnosis of uveal melanoma and vasoproliferative tumors is crucial
Management
- Consider IL-6 inhibitors for noninfectious uveitis
- Incorporate PDS for treatment of neovascular age-related macular degeneration
Monitoring & Follow-up
- Implement AI tools for monitoring progression of retinopathy of prematurity
Risks
- Be aware of safety setbacks associated with PDS post-approval
Patient & Prescribing Data
Patients with retinal disorders requiring innovative treatment options
Emerging therapies and technologies are being explored to enhance patient outcomes
Clinical Best Practices
- Stay updated on the latest innovations in retinal treatments
- Engage in continuous education through conferences and peer discussions
- Accurately code clinical findings to support medical necessity for treatments
References
