Reflections from ASRS
Upfront: Monthly reflection by Editor in Chief Diana V. Do, MD.
By
Diana V. Do, MD
September 1, 2025
Clinical Scorecard: Reflections from ASRS
At a Glance
Category Detail
Condition Retinal disorders including uveitis, ocular oncology, and pediatric retina
Key Mechanisms Emerging treatments and technologies including IL-6 inhibitors and AI in ROP care
Target Population Patients with vision-threatening retinal disorders
Care Setting Ophthalmology clinics and surgical settings
Key Highlights
Importance of timely diagnosis and management of vasoproliferative tumors Advancements in AI for standardizing ROP diagnosis and monitoring Current investigations into IL-6 inhibitors for noninfectious uveitis Challenges and efficacy of the port delivery system (PDS) for ranibizumab Adaptation of PDS for novel therapeutics in retinal diseases
Guideline-Based Recommendations
Diagnosis
Utilize advanced imaging and AI systems for accurate retinal diagnoses Timely diagnosis of uveal melanoma and vasoproliferative tumors is crucial
Management
Consider IL-6 inhibitors for noninfectious uveitis Incorporate PDS for treatment of neovascular age-related macular degeneration
Monitoring & Follow-up
Implement AI tools for monitoring progression of retinopathy of prematurity
Risks
Be aware of safety setbacks associated with PDS post-approval
Patient & Prescribing Data
Patients with retinal disorders requiring innovative treatment options
Emerging therapies and technologies are being explored to enhance patient outcomes
Clinical Best Practices
Stay updated on the latest innovations in retinal treatments Engage in continuous education through conferences and peer discussions Accurately code clinical findings to support medical necessity for treatments
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