Elevated triglyceride glucose-body mass index is associated with a higher risk of reduced cumulative live birth and adverse pregnancy outcomes in women undergoing assisted reproductive technology: a retrospective cohort study - Scorecard - MDSpire

Elevated triglyceride glucose-body mass index is associated with a higher risk of reduced cumulative live birth and adverse pregnancy outcomes in women undergoing assisted reproductive technology: a retrospective cohort study

  • By

  • Jie Hu

  • Shujuan Ma

  • Yinyan Gao

  • Yangqin Peng

  • Xiaojuan Wang

  • Irene X. Y. Wu

  • Fei Gong

  • June 17, 2026

  • 0 min

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Clinical Scorecard: Association of Elevated Triglyceride Glucose-Body Mass Index with Increased Risk of Lower Cumulative Live Birth Rates and Adverse Pregnancy Outcomes in Women Receiving Assisted Reproductive Technology: A Retrospective Cohort Analysis

At a Glance

CategoryDetail
ConditionInsulin resistance and reproductive outcomes
Key MechanismsTyG-BMI as a marker of insulin resistance
Target PopulationWomen undergoing ART
Care SettingReproductive and Genetic Hospital of CITIC-Xiangya, China

Key Highlights

  • Higher TyG-BMI is associated with lower cumulative live birth rates.
  • Increased risks of first-trimester miscarriage and second- or third-trimester fetal loss linked to higher TyG-BMI.

Guideline-Based Recommendations

Diagnosis

  • Use TyG-BMI as a marker for insulin resistance in ART patients.

Management

  • Monitor TyG-BMI in women undergoing ART.

Monitoring & Follow-up

  • Regular assessment of TyG-BMI in ART populations.

Risks

  • Higher TyG-BMI correlates with increased risks of miscarriage and fetal loss.

Patient & Prescribing Data

Women aged 20 to 45 years undergoing ART

Clinical Best Practices

  • Incorporate TyG-BMI assessment in evaluations of women undergoing ART.

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