Meeting Report on an Integrated Research Agenda for Mosquito-Borne Arboviruses

Category	Detail
Condition	Mosquito-borne arbovirus (MBV) diseases including Dengue, chikungunya, yellow fever, and Zika
Key Mechanisms	Transmission primarily by Aedes mosquito species (Ae. aegypti and Ae. albopictus) influenced by ecological, economic, and social factors such as climate change, urbanization, and vector control limitations
Target Population	Global populations living in endemic and emerging areas, particularly in the Americas, Africa, and Asia
Care Setting	Public health and epidemic preparedness settings including academic, governmental, and global health organizations

Rapid expansion of MBV diseases driven by climate change, urbanization, global travel, poverty, and insufficient vector control
Significant increase in Dengue incidence with nearly half the world’s population at risk and record outbreaks in the Americas
Integrated multipathogen research and policy approaches are essential for effective MBV disease prevention, preparedness, and control

Utilize surveillance and early detection strategies to monitor MBV transmission and outbreaks
Incorporate multipathogen approaches to improve diagnostic accuracy and epidemic preparedness

Implement integrated vector control programs targeting primary vectors Ae. aegypti and Ae. albopictus
Leverage existing knowledge and systems to address social and ecological drivers of MBV transmission

Enhance global surveillance systems for early detection and monitoring of MBV spread
Employ evolutionary and viral adaptation studies to anticipate changes in disease burden and transmission

Recognize increased risk due to climate change, urbanization, and global travel facilitating vector expansion
Address deficiencies in water storage, sanitation, and vector control that contribute to outbreak severity

Populations in endemic and emerging MBV transmission areas, including vulnerable groups in urban and rural settings

Focus on prevention through vector control and vaccination where available; clinical management guided by disease severity and outbreak context

Adopt integrated, multipathogen surveillance and research frameworks to improve epidemic preparedness
Prioritize research and investment in social, ecological, and vector control factors influencing MBV disease dynamics
Collaborate across sectors including academia, government, NGOs, and industry for comprehensive MBV control strategies

Clinical Scorecard: Summary of a Collaborative Research Framework for Arboviruses Transmitted by Mosquitoes