Cobalt nanoparticles protect against endocrine disruption in response to multiple abiotic stresses in fish
By
Neeraj Kumar
Paritosh Kumar
S.A. Kochewad
Prem Kumar
Dilip Kumar Singh
Kotha Sammi Reddy
June 10, 2026
Clinical Scorecard: Cobalt Nanoparticles Mitigate Endocrine Disruption Induced by Various Abiotic Stressors in Fish
At a Glance
Category Detail
Condition Key Mechanisms Disruption of the hypothalamic-pituitary-gonadal axis affecting reproductive hormones and gamete quality Target Population Care Setting
Key Highlights
Cobalt nanoparticles (Co-NPs) improve reproductive hormones in fish under stress conditions. Optimal Co-NP supplementation levels are 0.4 and 0.6 mg kg-1 diet. Milt characteristics such as motility and velocity are enhanced with Co-NP treatment. Multiple abiotic stressors include arsenic, ammonia, low pH, and elevated temperature. Guideline-Based Recommendations
Diagnosis
Evaluate endocrine disruption through reproductive hormone levels and milt quality. Management
Supplement fish diets with cobalt nanoparticles at 0.4 and 0.6 mg kg-1. Monitoring & Follow-up
Assess reproductive hormone levels and milt characteristics regularly. Risks
Monitor for potential adverse effects of cobalt at higher concentrations. Patient & Prescribing Data
Anabas testudineus exposed to abiotic stressors.
Clinical Best Practices
Implement cobalt nanoparticle supplementation in aquaculture diets. Regularly monitor water quality and stressor levels in aquaculture settings. Related Resources & Content
