Epidemiology of bone cancer in Saudi Arabia: a nationwide population-based study (2004–2020)
By
Ibrahim G. Alghamdi
Hasan A Alaidarous
Murad I Alghamdi
Khalid A Alghamdi
Musharraf A Alghamdi
Mazen S Alghamdi
Anas A Alzahrani
Tariq A Alghamdi
Osama M Alomari
Khalid S Alghamdi
Mohammed M Alzahrani
Ragad A Alzahrani
Hazim H Alsadi
June 26, 2026
Clinical Scorecard: National Epidemiological Analysis of Bone Cancer in Saudi Arabia: A Population-Based Study from 2004 to 2020
At a Glance
Category Detail
Condition Bone Cancer Key Mechanisms Primary malignant tumors arising from bone and articular cartilage, including osteosarcoma, chondrosarcoma, and Ewing sarcoma. Target Population Saudi nationals diagnosed with primary malignant bone tumors from 2004 to 2020. Care Setting Population-based cancer surveillance
Key Highlights
Total of 2,275 primary bone cancer cases recorded in Saudi Arabia from 2004 to 2020. Male predominance with 57.9% of cases; bone cancer accounted for 2.0% of all cancers in males and 0.9% in females. Age-standardized incidence rates (ASIRs) higher in males (≈1.0 per 100,000) than females (≈0.7 per 100,000). Adolescent peak incidence observed in the 15–19-year age group. Regional variation in ASIRs, with higher rates in Al-Jouf and Najran. Guideline-Based Recommendations
Diagnosis
Utilize data from the Saudi Cancer Registry for accurate cancer diagnosis. Management
Implement multimodal treatment strategies for primary bone cancers. Monitoring & Follow-up
Enhance population-based cancer surveillance for ongoing epidemiological assessment. Risks
Consider sex, age, and geographic region as factors influencing bone cancer incidence. Patient & Prescribing Data
Saudi nationals diagnosed with primary malignant bone tumors.
Complex multimodal treatment may be required due to the nature of bone cancers.
Clinical Best Practices
Adopt standardized epidemiological methods for calculating incidence rates. Ensure comprehensive data collection for accurate cancer registry reporting. Related Resources & Content
