Impact of Maternal Asthma and Asthma Treatment During Pregnancy on Neurodevelopmental Outcomes: Findings from a Cohort Study of 179,024 Children - Scorecard - MDSpire
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Impact of Maternal Asthma and Asthma Treatment During Pregnancy on Neurodevelopmental Outcomes: Findings from a Cohort Study of 179,024 Children
Clinical Scorecard: Impact of Maternal Asthma and Asthma Treatment During Pregnancy on Neurodevelopmental Outcomes: Findings from a Cohort Study of 179,024 Children
At a Glance
Category
Detail
Condition
Maternal Asthma
Key Mechanisms
Asthma exacerbations during pregnancy and treatment with asthma medications.
Target Population
Pregnant women with asthma and their children.
Care Setting
Maternity and pediatric care.
Key Highlights
Asthma prevalence among pregnant women is 8–13%.
B2AA and ICS are considered safe for maternal and perinatal outcomes.
Potential associations between prenatal asthma treatment and neurodevelopmental disorders like ADHD and ASD.
Study included a large cohort of 179,024 children born in Wales.
Primary outcome was the record of special educational needs (SEN) in children.
Guideline-Based Recommendations
Diagnosis
Asthma defined by eligible Read codes recorded within 2 years prior to delivery.
Management
Continuation of asthma medication during pregnancy is recommended.
Monitoring & Follow-up
Children's neurodevelopmental outcomes should be monitored, especially for SEN.
Risks
Uncontrolled asthma poses risks to both maternal and fetal health.
Patient & Prescribing Data
179,024 children born to mothers registered with SAIL general practitioners.
12.4% of mothers had a record of asthma or asthma medication.
Clinical Best Practices
Utilize B2AA as first-line treatment for asthma in pregnancy.
Monitor for asthma exacerbations and adjust treatment as necessary.
Consider potential neurodevelopmental outcomes when prescribing asthma medications.
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