Response quality of large language models on periprosthetic fractures: A comparative evaluation of ChatGPT, Gemini, and Claude - Scorecard - MDSpire
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Evaluating the Quality of Responses from Large Language Models on Periprosthetic Fractures: A Comparison of ChatGPT, Gemini, and Claude

  • By

  • Buğra Can

  • Anıl Agar

  • İrfan Arslan

  • September 29, 2026

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Clinical Scorecard: Evaluating the Quality of Responses from Large Language Models on Periprosthetic Fractures: A Comparison of ChatGPT, Gemini, and Claude

At a Glance

CategoryDetail
ConditionPeriprosthetic Fractures
Key MechanismsAssessment and treatment informed by implant stability, bone stock, and fracture configuration.
Target PopulationPatients undergoing total hip and/or knee arthroplasty.
Care SettingTertiary university hospital

Key Highlights

  • LLMs can produce fluent text but may convey inaccurate information.
  • Periprosthetic femoral fractures are a major complication after total hip arthroplasty.
  • Standardized evaluation frameworks like Vancouver classification and UCS are used for treatment selection.
  • The study compared responses from ChatGPT, Gemini, and Claude to standardized patient questions.
  • Expert panel assessed the quality of responses based on accuracy, safety, and readability.

Guideline-Based Recommendations

Diagnosis

  • Use standardized questions to assess common patient concerns regarding periprosthetic fractures.

Management

  • Consider implant stability, bone stock, and fracture configuration in treatment decisions.

Monitoring & Follow-up

  • Evaluate responses for accuracy and safety when using LLMs for patient education.

Risks

  • Be aware of the potential for LLMs to provide misleading information.

Patient & Prescribing Data

Patients with periprosthetic fractures post-arthroplasty.

Responses from LLMs should be critically evaluated for accuracy.

Clinical Best Practices

  • Utilize established classification systems for periprosthetic fractures.
  • Engage in thorough assessment of patient inquiries before providing information.

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