Gender-Diverse Youths Report More Psychotic Symptoms - Scorecard - MDSpire

Gender-Diverse Youths Report More Psychotic Symptoms

  • By

  • Andrea Surnit

  • May 21, 2026

  • 4 min

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Clinical Scorecard: Gender-Diverse Youths Reported More Psychotic-Like Experiences

At a Glance

CategoryDetail
ConditionPsychotic-like experiences in gender-diverse youths
Key MechanismsBullying victimization and unsupportive gender-identity policy environments
Target PopulationGender-diverse youths, particularly those assigned female at birth
Care SettingClinical settings assessing mental health in adolescents

Key Highlights

  • Most gender-diverse youths scored higher on psychotic-like experiences than least gender-diverse youths.
  • Bullying victimization partially mediated the association between gender diversity and psychotic-like experiences.
  • Psychotic-like experiences increased over time among most gender-diverse youths in low-support policy environments.
  • The study utilized the Prodromal Questionnaire–Brief Child Version (PQ-BC) for assessment.
  • Findings suggest implications for psychosis-risk assessment in gender-diverse youths.

Guideline-Based Recommendations

Diagnosis

  • Consider the potential contribution of gender minority stress when assessing psychosis risk.

Management

  • Implement school anti-bullying interventions to support mental health.

Monitoring & Follow-up

  • Monitor psychotic-like experiences in gender-diverse youths, especially in unsupportive policy environments.

Risks

  • Increased risk for later psychotic disorders, suicidal behavior, and poor functional outcomes linked to psychotic-like experiences.

Patient & Prescribing Data

Gender-diverse youths aged around 13 years

Consider social environment and policy context in treatment planning.

Clinical Best Practices

  • Utilize longitudinal data to understand trends in psychotic-like experiences.
  • Assess bullying victimization as a factor in mental health evaluations.
  • Engage with supportive policy environments to improve mental health outcomes.

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