A comparative study of conventional, High-flow, and jet ventilation via the Wei nasal jet tube for oxygen therapy in patients undergoing bronchoscopic intervention under deep sedation: a randomized controlled trial - Scorecard - MDSpire

A comparative study of conventional, High-flow, and jet ventilation via the Wei nasal jet tube for oxygen therapy in patients undergoing bronchoscopic intervention under deep sedation: a randomized controlled trial

  • By

  • Ai-Di Zhang

  • Xiang Ge

  • Xiao-Li Li

  • Qing-Hao Cheng

  • Ming-Yuan Yang

  • June 24, 2026

  • 0 min

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Clinical Scorecard: A Randomized Controlled Trial Comparing Conventional Oxygen Therapy, High-Flow Nasal Cannula, and Jet Ventilation Using the Wei Nasal Jet Tube During Bronchoscopic Procedures Under Deep Sedation

At a Glance

CategoryDetail
ConditionHypoxemia during bronchoscopic interventions
Key MechanismsSupraglottic jet oxygenation and ventilation (SJOV) via Wei nasal jet tube (WNJ)
Target PopulationPatients with mild-to-moderate airway stenosis undergoing bronchoscopy
Care SettingEmergency General Hospital, Beijing, China

Key Highlights

  • SJOV showed a lower incidence of intraoperative hypoxemia compared to conventional oxygen therapy (COT)
  • Significantly higher PaO2 levels in the SJOV group than in COT and high-flow nasal cannula (HFNC) groups
  • SJOV resulted in lower lactic acid levels compared to both COT and HFNC
  • No significant differences in adverse events or procedure duration among the groups

Guideline-Based Recommendations

Diagnosis

  • Assess airway stenosis via preoperative computed tomography (CT)
  • Evaluate patient eligibility based on ASA classification II-III

Management

  • Utilize SJOV for oxygenation and ventilation in patients with mild-to-moderate airway stenosis during bronchoscopy

Monitoring & Follow-up

  • Monitor SpO2 and arterial blood gas parameters during procedures

Risks

  • Consider exclusion criteria such as severe airway stenosis and comorbid conditions affecting anesthesia

Patient & Prescribing Data

Adults aged 18-80 with mild-to-moderate airway stenosis

SJOV is a feasible option for oxygenation without increasing adverse events

Clinical Best Practices

  • Ensure informed consent is obtained from all participants
  • Conduct thorough preoperative assessments to identify suitable candidates for SJOV
  • Maintain hemodynamic stability and monitor for hypoxemia during procedures

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