Sphincter-saving surgery versus abdominoperineal resection in low rectal cancer: the role of indocyanine green fluorescence angiography in surgical decision-making - Scorecard - MDSpire

Sphincter-saving surgery versus abdominoperineal resection in low rectal cancer: the role of indocyanine green fluorescence angiography in surgical decision-making

  • By

  • Mihaela C. Misca

  • Sorin V. Petrea

  • Roxana D. Boanta

  • Sorin Aldoescu

  • Eduard Catrina

  • Mihaela E. Vilcu

  • V. Grigorean

  • V. Strambu

  • Iulian Brezean

  • July 9, 2026

  • 0 min

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Clinical Scorecard: Comparing Sphincter-Sparing Surgery and Abdominoperineal Resection for Low Rectal Cancer: The Impact of Indocyanine Green Fluorescence Angiography on Surgical Choices

At a Glance

CategoryDetail
ConditionLow Rectal Cancer
Key MechanismsIndocyanine green fluorescence angiography (ICG-FA) assesses bowel perfusion to prevent anastomotic failure.
Target PopulationPatients with low rectal cancer (≤6 cm from the anal verge).
Care SettingTertiary academic surgical department.

Key Highlights

  • ICG-FA modified the resection line in 40% of patients assessed.
  • Radical (R0) resection achieved in 19 of 21 patients with margin status recorded.
  • Postoperative complications occurred in 56% of patients, mostly Clavien–Dindo grade I–II.
  • No 30-day mortality reported; one late in-hospital death occurred beyond 30 days.
  • Sphincter-saving surgery is feasible but carries substantial morbidity.

Guideline-Based Recommendations

Diagnosis

  • Histologically proven colorectal adenocarcinoma.

Management

  • Consider sphincter-saving surgery versus abdominoperineal resection based on tumor characteristics and patient factors.

Monitoring & Follow-up

  • Postoperative assessment for complications, particularly anastomotic leaks.

Risks

  • Inadequate perfusion of the proximal colonic stump is a leading cause of anastomotic failure.

Patient & Prescribing Data

Patients undergoing surgery for low rectal cancer.

ICG-FA is a low-risk adjunct that informs intraoperative decision-making.

Clinical Best Practices

  • Utilize ICG-FA in all sphincter-saving procedures for low rectal cancer.
  • Integrate tumor-related and patient-related variables in surgical decision-making.

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