Outcomes of Phacoemulsification and Trabeculectomy for Uncontrolled Glaucoma and Cataract: A Comparison of Staged and Combined Techniques in a Single-Center Observational Study - Scorecard - MDSpire
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Outcomes of Phacoemulsification and Trabeculectomy for Uncontrolled Glaucoma and Cataract: A Comparison of Staged and Combined Techniques in a Single-Center Observational Study

  • By

  • Matteo Sacchi

  • Gianluca Monsellato

  • Davide Rastelli

  • Shadan Ranaei

  • Davide Tomaselli

  • Gaia Li Calzi

  • Edoardo Villani

  • Stefano Dore

  • Antonio Pinna

  • Paolo Nucci

  • February 9, 2026

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Clinical Scorecard: Outcomes of Phacoemulsification and Trabeculectomy for Uncontrolled Glaucoma and Cataract: A Comparison of Staged and Combined Techniques in a Single-Center Observational Study

At a Glance

CategoryDetail
ConditionUncontrolled glaucoma with coexisting cataract
Key MechanismsPhacoemulsification reduces IOP; Trabeculectomy stabilizes IOP
Target PopulationAdults with uncontrolled glaucoma and significant cataract
Care SettingOphthalmic Clinic, San Giuseppe Hospital, Milan, Italy

Key Highlights

  • Staged approach associated with lower mean IOP and higher success rates
  • Combined approach minimizes postoperative IOP spikes
  • No strict guidelines on preferred surgical approach
  • Postoperative IOP control comparable between combined and trabeculectomy alone
  • Need for longer-term outcomes to assess IOP maintenance

Guideline-Based Recommendations

Diagnosis

  • Uncontrolled glaucoma defined by specific criteria
  • Coexisting clinically significant cataract

Management

  • Consider staged or combined surgical approaches based on individual patient factors
  • Evaluate surgeon experience and patient preference

Monitoring & Follow-up

  • Follow-up for at least 4 years post-surgery to assess IOP and medication use

Risks

  • Postoperative rise in IOP after phacoemulsification
  • Higher complication rates with combined surgery

Patient & Prescribing Data

Adults with uncontrolled glaucoma and significant cataract

Both surgical approaches lead to IOP reduction; choice depends on individual clinical characteristics

Clinical Best Practices

  • Assess individual patient characteristics before deciding on surgical approach
  • Monitor IOP closely post-surgery to manage potential spikes
  • Consider patient preference for single vs. multiple interventions

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