Longitudinal trajectories of urinary albumin-to-creatinine ratio and risk of proteinuria among Chinese patients with type 2 diabetes: a single−center retrospective cohort study - Scorecard - MDSpire

Longitudinal trajectories of urinary albumin-to-creatinine ratio and risk of proteinuria among Chinese patients with type 2 diabetes: a single−center retrospective cohort study

  • By

  • Qian Chen

  • Tieqiao Wang

  • Xiaoqing Tian

  • Qiankai Jin

  • Li Li

  • Yushan Mao

  • Guoqing Huang

  • June 2, 2026

  • 0 min

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Clinical Scorecard: Patterns of Urinary Albumin-to-Creatinine Ratio Over Time and Their Association with Proteinuria Risk in Chinese Individuals with Type 2 Diabetes: A Retrospective Cohort Analysis from a Single Center

At a Glance

CategoryDetail
Condition
Key MechanismsUrinary albumin-to-creatinine ratio (UACR) as a marker for proteinuria progression (source needed)
Target Population
Care Setting

Key Highlights

  • Significant proteinuria risk associated with mid-range normal (HR = 48.40, 95% CI: 14.67-159.67) and rising with fluctuation groups (HR = 509.56, 95% CI: 157.01–1653.70).

Guideline-Based Recommendations

Diagnosis

    Management

    • Regular monitoring of UACR to assess proteinuria risk in T2DM patients (source needed).

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        3,101 T2DM patients with baseline UACR <30 mg/g.

        Identifying UACR trajectory patterns can enhance early-stage diabetic kidney disease screening.

        Clinical Best Practices

        • Implement trajectory-informed patient classification for early identification of high-risk individuals (source needed).

        Related Resources & Content

        Original Source(s)

        Longitudinal trajectories of urinary albumin-to-creatinine ratio and risk of proteinuria among Chinese patients with type 2 diabetes: a single−center retrospective cohort study

        • by Qian Chen, Tieqiao Wang, Xiaoqing Tian, Qiankai Jin, Li Li, Yushan Mao, Guoqing Huang

        • June 2, 2026

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