Transseptal Thrombus Across a Patent Foramen Ovale: A Clinical Case Study
By
Qin Jiangyan
Dan Li
Shi Mengrong
Hu Zitao
July 7, 2026
Clinical Scorecard: Transseptal Thrombus Across a Patent Foramen Ovale: A Clinical Case Study
At a Glance
Category Detail
Condition Transseptal Thrombus Across a Patent Foramen Ovale Key Mechanisms Paradoxical embolism due to a patent foramen ovale allowing venous emboli to cross from the right to the left atrium. Target Population Patients with patent foramen ovale and suspected thromboembolic events. Care Setting Emergency and inpatient care settings.
Key Highlights
Transseptal thrombus is a rare but critical finding indicating potential paradoxical embolism. Contrast-enhanced cardiac CT is vital for diagnosing transseptal thrombus. Anticoagulation therapy was successfully implemented in the reported case. Guideline-Based Recommendations
Diagnosis
Use contrast-enhanced CT angiography for identifying transseptal thrombus. Management
Initiate anticoagulation therapy as the primary management strategy. Monitoring & Follow-up
Follow-up assessments at 1, 3, 6, 12 months post-discharge to monitor for symptoms and adherence. Risks
Consider the risks of thrombolysis and surgery versus the benefits of anticoagulation. Patient & Prescribing Data
Elderly patients with acute dyspnea and evidence of thromboembolism.
Rivaroxaban was prescribed, starting at 15 mg twice daily, transitioning to 20 mg once daily.
Clinical Best Practices
Ensure timely recognition of transseptal thrombus to prevent systemic embolism. Engage in shared decision-making with patients regarding management options. Related Resources & Content
