Teacher-rated childhood emotional, behavioural and social problems and alcohol-related, drug-related and intentional self-harm-related hospitalisation and mortality in adulthood (18–40 years): a population-based cohort study - Scorecard - MDSpire
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Teacher-Assessed Emotional, Behavioural and Social Difficulties in Childhood and Alcohol-Related, Drug-Related and Intentional Self-Harm Hospitalisations and Deaths in Adulthood (Ages 18–40): A Population-Based Cohort Study

  • By

  • Minjae Choi

  • Sylvana M Côté

  • Caroline E Temcheff

  • Marc Dorais

  • Frank Vitaro

  • Richard E Tremblay

  • Marie-Claude Geoffroy

  • October 13, 2026

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Clinical Scorecard: Teacher-Assessed Childhood Socioemotional Difficulties and Adult Diseases of Despair

At a Glance

CategoryDetail
ConditionClinical topic addressed by the source article: Teacher-Assessed Emotional, Behavioural and Social Difficulties in Childhood and Alcohol-Related, Drug-Related and Intentional Self-Harm Hospitalisations and Deaths in Adulthood (Ages 18–40)
Key MechanismsMechanisms or clinical associations described in the source article.
Target PopulationPopulation-based cohort of 5,290 individuals enrolled at age 6; teachers assessed socioemotional difficulties at ages 6–12, and linked records captured hospitalisations and deaths between ages 18 and 40.
Care SettingCare setting described in the source article.

Key Highlights

  • A 1-SD increase in overall childhood emotional, behavioural and social problems was associated with a 49% higher hazard of adult diseases of despair (adjusted HR 1.49; 95% CI 1.32–1.68).
  • Disruptive behaviours and ADHD symptoms were associated with higher hazards (adjusted HR 1.39 and 1.44, respectively).
  • Greater prosociality was associated with a lower hazard (adjusted HR 0.81; 95% CI 0.71–0.93).
  • Associations were concentrated largely in alcohol- and drug-related diseases; disruptive-behaviour associations were stronger among females.
  • By age 40, 4.7% of participants had experienced hospitalisation or death from diseases of despair.

Guideline-Based Recommendations

Diagnosis

  • The study assessed childhood socioemotional difficulties through teacher ratings of disruptive behaviours, ADHD symptoms, emotional distress and prosociality.
  • Adult outcomes were identified through linked health records and included hospitalisation or death from alcohol-related disease, drug-related disease or intentional self-harm.

Management

  • The authors state that intervention studies are needed to assess whether altering childhood socioemotional capacities lowers later risk.

Monitoring & Follow-up

  • The cohort was followed for adult hospitalisations and deaths from ages 18 to 40.

Risks

  • Higher overall childhood socioemotional difficulty scores, disruptive behaviours and ADHD symptoms were associated with higher adult diseases-of-despair hazards.
  • The reported associations are observational and do not establish that childhood difficulties cause adult outcomes.

Patient & Prescribing Data

The Québec Longitudinal Study of Kindergarten Children included 5,290 individuals enrolled at age 6; teachers assessed socioemotional difficulties during ages 6–12.

No treatment or prescribing data were reported. The authors call for intervention studies to test whether changing childhood socioemotional capacities affects later risk.

Clinical Best Practices

  • The study found observational associations between childhood socioemotional difficulties and adult hospitalisation or death from alcohol-related disease, drug-related disease or intentional self-harm between ages 18 and 40; it does not establish causation.
  • The authors state that childhood socioemotional difficulties could help flag people facing greater long-term vulnerability, but provide no clinical screening protocol.

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