Clinical Scorecard: Clinical Case Study: Adolescent Patient with Invasive Encapsulated Follicular Variant of Papillary Thyroid Carcinoma and Review of Existing Literature
At a Glance
Category
Detail
Condition
Invasive Encapsulated Follicular Variant of Papillary Thyroid Carcinoma (IEFVPTC)
Key Mechanisms
Well-differentiated malignant thyroid tumor with a RAS-like molecular profile and tendency for hematogenous metastasis.
Target Population
Adolescents, particularly rare cases in females.
Care Setting
Thyroid surgery department
Key Highlights
IEFVPTC is recognized as an independent entity in the 2022 WHO classification.
Ultrasound features may mimic benign nodules, necessitating vigilance.
Surgical management typically involves lobectomy for tumors <4 cm without vascular invasion.
Guideline-Based Recommendations
Diagnosis
Ultrasound is the preferred screening modality.
Fine-needle aspiration biopsy is required for definitive diagnosis.
Management
Lobectomy is sufficient for tumors <4 cm without vascular invasion.
Monitoring & Follow-up
Thyroid function tests should be conducted every three months post-surgery.
Risks
Potential for misdiagnosis due to benign ultrasound features.
Patient & Prescribing Data
Adolescents with IEFVPTC.
Preoperative oral methimazole therapy was used to control thyroid function.
Clinical Best Practices
Heightened vigilance for hypervascular nodules in adolescents.
Tailor surgical extent to the degree of invasiveness.
