Letter to the Editor: “Organ donation after ECPR: ethical challenges and clinical implications” - Scorecard - MDSpire
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Correspondence to the Editor: “Ethical Considerations and Clinical Consequences of Organ Donation Following ECPR”

  • By

  • Jose Moya Sánchez

  • Beatriz Domínguez-Gil

  • Jose Miguel Pérez Villares

  • Mario Royo-Villanova

  • August 27, 2026

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Clinical Scorecard: Ethical Considerations and Clinical Consequences of Organ Donation Following ECPR

At a Glance

CategoryDetail
ConditionOrgan Donation After ECPR
Key MechanismsEthical framework for organ donation, separation of clinical decisions and donation considerations, procedural safeguards in DCDD programs.
Target PopulationPatients undergoing ECPR and their families.
Care SettingIntensive Care Unit

Key Highlights

  • ECPR should be performed solely for therapeutic purposes.
  • Decisions on treatment limitation must remain separate from donation considerations.
  • Communication about donation should follow clear understanding of clinical prognosis.
  • Procedural safeguards are essential to prevent undue influence on clinical decisions.
  • Clarification of the Dead Donor Rule is necessary in the context of DCDD.

Guideline-Based Recommendations

Diagnosis

  • Ensure clear communication of clinical situation and prognosis before discussing donation.

Management

  • Maintain separation between end-of-life decisions and donation procedures.

Monitoring & Follow-up

  • Implement rigorous technical safeguards during normothermic regional perfusion.

Risks

  • Address potential pressures related to financial and resource incentives in donation.

Patient & Prescribing Data

Patients eligible for organ donation post-ECPR.

Informed consent from family or legal representatives is crucial before proceeding with donation.

Clinical Best Practices

  • Establish robust protocols for DCDD to ensure ethical compliance.
  • Sequence communication about prognosis and donation appropriately.
  • Conduct ongoing research to validate technical standards in organ donation.

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