Impact of cerebral small vessel disease burden and systemic clinical phenotypes on short-term neurological outcomes after acute ischemic stroke - Scorecard - MDSpire

Impact of cerebral small vessel disease burden and systemic clinical phenotypes on short-term neurological outcomes after acute ischemic stroke

  • By

  • Lifang Ma

  • Fangtong Liu

  • Jing Deng

  • Fangyuan Cui

  • Jing Bai

  • Bin Ma

  • Lu Tang

  • Xiao Han

  • Li Zhou

  • Ying Gao

  • Yan Li

  • June 4, 2026

  • 0 min

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Clinical Scorecard: Influence of Cerebral Small Vessel Disease Severity and Systemic Clinical Characteristics on Immediate Neurological Recovery Following Acute Ischemic Stroke

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationPatients with acute ischemic stroke admitted to Dongzhimen Hospital, Beijing University of Chinese Medicine.
Care SettingHospital setting, specifically a stroke unit with a focus on acute care.

Key Highlights

  • Higher total CSVD burden is associated with unfavorable neurological outcomes, particularly in patients with hyperhomocysteinemia and specific Traditional Chinese Medicine phenotypes.

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

      • Monitor NIHSS scores at discharge and establish follow-up protocols based on score changes.

      Risks

        Patient & Prescribing Data

        Patients with unfavorable outcomes had a higher total CSVD burden and specific systemic characteristics, including hyperhomocysteinemia.

        Clinical Best Practices

        • Utilize MRI to evaluate CSVD markers in AIS patients and incorporate systemic clinical assessments in evaluating stroke outcomes, ensuring integration into clinical workflows.

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        Original Source(s)

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