Prevalence and influencing factors of cognitive frailty in patients with chronic heart failure: a meta-analysis - Scorecard - MDSpire

Cognitive Frailty in Chronic Heart Failure Patients: A Meta-Analysis of Prevalence and Contributing Factors

  • By

  • Meiwan Zhang

  • Chen Zhou

  • Min Hu

  • Chi Tian

  • Jiayue Zeng

  • July 20, 2026

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Clinical Scorecard: Cognitive Frailty in Chronic Heart Failure Patients: A Meta-Analysis of Prevalence and Contributing Factors

At a Glance

CategoryDetail
ConditionCognitive Frailty in Chronic Heart Failure
Key MechanismsConcurrent physical and cognitive impairment, influenced by various risk factors.
Target PopulationPatients with chronic heart failure.
Care SettingClinical settings for chronic heart failure management.

Key Highlights

  • Pooled prevalence of cognitive impairment in CHF patients is 39.3%.
  • Significant risk factors include age, NYHA classification, and polypharmacy.
  • Protective factors include higher educational attainment and regular physical exercise.

Guideline-Based Recommendations

Diagnosis

  • Routine cognitive function screening for chronic heart failure patients.

Management

  • Implement targeted interventions based on identified risk factors.

Monitoring & Follow-up

  • Monitor cognitive function regularly to identify high-risk patients.

Risks

  • Cognitive frailty is associated with higher mortality and readmission rates.

Patient & Prescribing Data

Patients diagnosed with chronic heart failure, regardless of age or gender.

Focus on addressing modifiable risk factors to improve cognitive outcomes.

Clinical Best Practices

  • Strengthen routine cognitive screening in CHF management.
  • Encourage physical activity and intellectual engagement among patients.

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