Impact of standardized fortified donor human milk on growth parameters and biomarkers in preterm very low birth weight infants: a single-center propensity score-matched analysis - Scorecard - MDSpire
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Effects of Standardized Fortified Donor Human Milk on Growth Metrics and Biomarkers in Preterm Infants with Very Low Birth Weight: A Propensity Score-Matched Study from a Single Center
Clinical Scorecard: Effects of Standardized Fortified Donor Human Milk on Growth Metrics and Biomarkers in Preterm Infants with Very Low Birth Weight: A Propensity Score-Matched Study from a Single Center
At a Glance
Category
Detail
Condition
Preterm Very Low Birth Weight Infants
Key Mechanisms
Standardized Fortified Donor Human Milk (SF-DHM) improves growth parameters and nutritional biomarkers.
Target Population
Preterm infants with birth weight <1,500 g hospitalized in NICU.
Care Setting
Neonatal Intensive Care Unit (NICU)
Key Highlights
SF-DHM leads to superior weight gain and growth velocities compared to conventional feeding.
Lower incidence of extrauterine growth restriction at discharge in the SF-DHM group.
Improved nutritional biomarkers and reduced inflammatory markers observed with SF-DHM.
Lower rates of feeding intolerance and complications in the SF-DHM group.
Guideline-Based Recommendations
Diagnosis
Identify preterm infants with very low birth weight for nutritional intervention.
Management
Implement SF-DHM as a primary nutritional source for VLBW infants with insufficient maternal milk.
Monitoring & Follow-up
Regularly assess growth parameters and nutritional biomarkers during hospitalization.
Risks
Monitor for potential feeding intolerance and complications associated with nutritional interventions.
Patient & Prescribing Data
Preterm infants with gestational age <32 weeks and birth weight <1,500 g.
SF-DHM is a safe and effective enteral nutrition strategy for VLBW infants.
Clinical Best Practices
Prioritize the use of SF-DHM in the nutritional management of preterm infants.
Ensure systematic treatment and enteral feeding initiation after clinical stabilization.
