Paradoxical enrichment of Akkermansia in children with poorly controlled asthma: a longitudinal study
Clinical Scorecard: Unexpected Increase of Akkermansia in Pediatric Patients with Uncontrolled Asthma: A Longitudinal Analysis
At a Glance
| Category | Detail |
|---|
| Condition | |
| Key Mechanisms | Intestinal dysbiosis and gut microbiota composition related to asthma severity. |
| Target Population | |
| Care Setting | |
Key Highlights
- Intensive corticosteroid treatment may influence gut microbiome composition.
Guideline-Based Recommendations
Diagnosis
Management
- Consider the impact of gut microbiota on asthma severity.
- Tailor treatments based on individual microbiome profiles, particularly for different asthma phenotypes.
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Pediatric patients with asthma aged 6-14 years.
Microbiome-targeted therapies should consider asthma phenotypes and prior medication usage.
Clinical Best Practices
- Incorporate routine gut microbiota assessments in asthma management.
Related Resources & Content
