Holding vs Continuing GLP-1/GIP Agonists Before Upper Endoscopy: The OCULUS Randomized Clinical Trial - Scorecard - MDSpire

Holding vs Continuing GLP-1/GIP Agonists Before Upper Endoscopy: The OCULUS Randomized Clinical Trial

  • By

  • Akram I. Ahmad

  • Samita Garg

  • Jeffrey Jacobs

  • Zaid Ansari

  • Tasneem Jamal Al-Din

  • Ashraf Almomani

  • Sara Valencia

  • John Vargo

  • Arjun Chatterjee

  • Hassan Siddiki

  • Liang Hong

  • Michael A. Nicolas

  • Alaina Miller

  • Tilak Shah

  • May 1, 2026

  • 0 min

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Clinical Scorecard: Comparison of Discontinuing versus Continuing GLP-1/GIP Agonists Prior to Upper Endoscopy: Findings from the OCULUS Randomized Clinical Trial

At a Glance

CategoryDetail
Condition
Key MechanismsDelayed gastric emptying, inhibition of acetylcholine release, increased nitric oxide production, modulation of GABAergic pathways (add references).
Target Population
Care Setting

Key Highlights

  • primary_outcome

Guideline-Based Recommendations

Diagnosis

    Management

    • C
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    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Rationale for holding medications based on evidence from the source.

        Clinical Best Practices

        • fasting_instructions

        References

        Original Source(s)

        Holding vs Continuing GLP-1/GIP Agonists Before Upper Endoscopy: The OCULUS Randomized Clinical Trial

        • by Akram I. Ahmad, Samita Garg, Jeffrey Jacobs, Zaid Ansari, Tasneem Jamal Al-Din, Ashraf Almomani, Sara Valencia, John Vargo, Arjun Chatterjee, Hassan Siddiki, Liang Hong, Michael A. Nicolas, Alaina Miller, Tilak Shah

        • May 1, 2026

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