Fibrinogen-to-red blood cell ratio is associated with disease burden and short-term outcomes in hospitalized patients with gout: comparison with conventional inflammatory indices - Scorecard - MDSpire

Fibrinogen-to-red blood cell ratio is associated with disease burden and short-term outcomes in hospitalized patients with gout: comparison with conventional inflammatory indices

  • By

  • Hao-Jie Zhong

  • Shu-Juan Chen

  • Xiao-Lan Qian

  • Min Xiao

  • Gui-Chen Ling

  • Jian-Yong Zhang

  • Jing-Jing Xie

  • July 15, 2026

Share

Clinical Scorecard: Association of Fibrinogen-to-Red Blood Cell Ratio with Disease Severity and Short-Term Outcomes in Hospitalized Gout Patients: A Comparison with Traditional Inflammatory Markers

At a Glance

CategoryDetail
ConditionGout
Key MechanismsFibrinogen-to-red blood cell ratio (FRR) as a biomarker for inflammatory status and disease burden.
Target PopulationHospitalized patients with gout.
Care SettingDepartment of Rheumatology, Shenzhen Traditional Chinese Medicine Hospital.

Key Highlights

  • High FRR associated with increased annual flares and tophi prevalence.
  • Stronger correlation of FRR with CRP and ESR compared to NLR and PLR.
  • High FRR linked to higher hospitalization costs and 30-day readmission rates.

Guideline-Based Recommendations

Diagnosis

  • Use 2015 ACR/EULAR gout classification criteria for diagnosis.

Management

  • Consider FRR as an adjunctive biomarker for assessing disease burden and inflammatory activity.

Monitoring & Follow-up

  • Monitor FRR alongside traditional inflammatory markers like CRP and ESR.

Risks

  • High FRR may indicate increased risk of complications such as proteinuria and longer hospital stays.

Patient & Prescribing Data

330 hospitalized patients with gout.

Data on medication use at admission includes corticosteroids, colchicine, NSAIDs, and urate-lowering therapy.

Clinical Best Practices

  • Integrate FRR into clinical assessments for hospitalized gout patients.
  • Utilize comprehensive inflammatory markers for better disease characterization.

Related Resources & Content

Original Source(s)

Related Content