Heart Failure with Preserved Ejection Fraction Viewed as a Systemic Inflammatory-Metabolic Condition: Insights from the Cardio-Hepato-Pancreatic Axis - Scorecard - MDSpire

Heart Failure with Preserved Ejection Fraction Viewed as a Systemic Inflammatory-Metabolic Condition: Insights from the Cardio-Hepato-Pancreatic Axis

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  • Han Naung Tun

  • April 28, 2026

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Clinical Scorecard: Heart Failure with Preserved Ejection Fraction Viewed as a Systemic Inflammatory-Metabolic Condition: Insights from the Cardio-Hepato-Pancreatic Axis

At a Glance

CategoryDetail
Condition
Key MechanismsSystemic inflammation and metabolic dysfunction affecting the cardiovascular system, supported by recent studies.
Target Population
Care Setting

Key Highlights

  • Add references to studies supporting the efficacy of SGLT2 inhibitors and GLP-1 receptor agonists.

Guideline-Based Recommendations

Diagnosis

    Management

    • Focus on interventions that target congestion, inflammation, and metabolic dysregulation, with specific examples.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Patients with HFpEF, particularly those with comorbidities like obesity and diabetes.

        SGLT2 inhibitors and GLP-1 receptor agonists may provide systemic benefits beyond heart function.

        Clinical Best Practices

        • Provide specific examples of how each specialty (cardiology, hepatology, gastroenterology) contributes to patient care.

        References

        Original Source(s)

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