Inaugural year of regulated psilocybin services in Oregon: safety, motivations, and utilization - Scorecard - MDSpire

Inaugural year of regulated psilocybin services in Oregon: safety, motivations, and utilization

  • By

  • Feliciano Yu

  • Joe Tafur

  • Francisco Moreno

  • Stephen Dahmer

  • May 13, 2026

  • 0 min

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Clinical Scorecard: First Year of Regulated Psilocybin Services in Oregon: An Analysis of Safety, User Motivations, and Service Utilization

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target Population
Care Setting

Key Highlights

  • 5,935 clients participated in 5,375 sessions in 2025
  • 32.6% of participants were from outside Oregon
  • Majority of clients aged 35-49, with significant representation of women and LGBQ+ individuals
  • Adverse events were rare, with rates of 2.42 behavioral and 2.79 medical per 1,000 sessions
  • Racial diversity among participants was limited, with 84.1%-91.5% being White

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

        Risks

        • Monitor for adverse behavioral and medical reactions during sessions
        • Implement strategies to improve racial diversity among participants

        Patient & Prescribing Data

        Adults seeking psilocybin services for wellness and mental health

        Participants reported motivations including wellness, mental health, trauma, and spiritual growth

        Clinical Best Practices

        • Ensure administration in controlled settings to maximize safety
        • Implement thorough screening and intention setting prior to sessions
        • Facilitate integration sessions to discuss experiences post-administration

        Related Resources & Content

        Original Source(s)

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