Associations of CALLY, CLR, and CHR with all-cause mortality in patients receiving maintenance hemodialysis: a two-center retrospective cohort study - Scorecard - MDSpire

Associations of CALLY, CLR, and CHR with all-cause mortality in patients receiving maintenance hemodialysis: a two-center retrospective cohort study

  • By

  • Ying Xu

  • Yujian He

  • Yuting Liu

  • Yanting Liang

  • Guanghao Wei

  • Zhen Wang

  • Nan Hu

  • Lijun Luo

  • Hualin Ma

  • Xinzhou Zhang

  • July 6, 2026

  • 0 min

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Clinical Scorecard: Links Between CALLY, CLR, and CHR Indices and Overall Mortality in Patients Undergoing Maintenance Hemodialysis: A Retrospective Cohort Analysis from Two Centers

At a Glance

CategoryDetail
ConditionMaintenance Hemodialysis (MHD)
Key MechanismsInflammation-related indices (CALLY, CLR, CHR) associated with mortality risk.
Target PopulationAdult patients undergoing maintenance hemodialysis.
Care SettingRetrospective cohort study in two hemodialysis centers.

Key Highlights

  • CALLY index associated with lower mortality risk (HR 0.85).
  • CLR and CHR indices associated with higher mortality risk (HR 1.19 and HR 1.18, respectively).
  • Significant survival differences observed across tertiles of indices.
  • Three-year AUCs for ln CALLY, ln CLR, and ln CHR were 0.603, 0.598, and 0.563.
  • Study included 540 patients followed for a median of 36.67 months.

Guideline-Based Recommendations

Diagnosis

  • Evaluate inflammation-related indices (CALLY, CLR, CHR) for prognostic risk stratification.

Management

  • Monitor inflammation-related indices as part of routine care in MHD patients.

Monitoring & Follow-up

  • Follow changes in CALLY, CLR, and CHR indices over time to assess mortality risk.

Risks

  • Higher CLR and CHR values are associated with increased mortality risk.

Patient & Prescribing Data

Patients undergoing maintenance hemodialysis for at least 3 months.

Indices derived from routine laboratory parameters may aid in risk stratification.

Clinical Best Practices

  • Incorporate CALLY, CLR, and CHR indices into clinical assessments for MHD patients.
  • Utilize composite indices for a comprehensive evaluation of patient status.

Related Resources & Content

    Original Source(s)

    Associations of CALLY, CLR, and CHR with all-cause mortality in patients receiving maintenance hemodialysis: a two-center retrospective cohort study

    • by Ying Xu, Yujian He, Yuting Liu, Yanting Liang, Guanghao Wei, Zhen Wang, Nan Hu, Lijun Luo, Hualin Ma, Xinzhou Zhang

    • July 6, 2026

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