A Case Study of Myofibroblast Accumulation in a Carotid Web - Scorecard - MDSpire

A Case Study of Myofibroblast Accumulation in a Carotid Web

  • By

  • Saki Kotani

  • Ryoji Yasumizu

  • Yasuhiro Takeuchi

  • Takumi Yamanaka

  • Kazuyuki Kuwayama

  • Keigo Matsumoto

  • February 7, 2026

  • 0 min

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Clinical Scorecard: A Case Study of Myofibroblast Accumulation in a Carotid Web

At a Glance

CategoryDetail
Condition
Key MechanismsIntraluminal fibrous protrusion causing turbulence and stasis of blood flow, leading to thrombus formation and increased risk of embolic stroke.
Target Population
Care Setting

Key Highlights

  • Carotid webs are associated with a 10-fold increased risk of ischemic stroke in young patients.
  • Symptomatic carotid web has a recurrence rate of stroke reported between 29-56% within 2 years.
  • Optimal management remains unclear; antithrombotic therapy is first-line for symptomatic cases, with uncertainty for asymptomatic cases.

Guideline-Based Recommendations

Diagnosis

    Management

    • Antithrombotic therapy is recommended for symptomatic cases; CEA or CAS may be considered, but treatment for asymptomatic cases is generally observation.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Aspirin therapy is commonly initiated, though the necessity for treatment in asymptomatic cases is debated and remains controversial.

        Clinical Best Practices

        • Consider early procedural intervention for symptomatic carotid web, as recent evidence suggests this may be beneficial.

        References

        Original Source(s)

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