Advancing human ovarian biology in tandem with clinical care: considerations for collecting ovarian tissue for research after oophorectomy for tissue cryopreservation - Scorecard - MDSpire

Advancing human ovarian biology in tandem with clinical care: considerations for collecting ovarian tissue for research after oophorectomy for tissue cryopreservation

  • By

  • Margaret A. Brunette

  • Karen Burns

  • Holly Hoefgen

  • Shuo Xiao

  • Francesca E. Duncan

  • Monica M. Laronda

  • Ariella Shikanov

  • Mary Zelinski

  • Veronica Gomez-Lobo

  • June 3, 2026

  • 0 min

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Clinical Scorecard: Enhancing Understanding of Ovarian Biology Through Clinical Practice: Key Considerations for Ovarian Tissue Collection Post-Oophorectomy for Cryopreservation Research

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target Population
Care Setting

Key Highlights

  • OTC is no longer considered experimental as of 2019.
  • Research tissue samples provide insights into ovarian biology and reproductive dysfunction.
  • Informed consent is crucial, detailing tissue use and research parameters.
  • Different tissue collection methods impact the quality and type of analyses possible.
  • Flash freezing is the gold standard for certain 'omics' research.

Guideline-Based Recommendations

Diagnosis

    Management

    • Prioritize patient use of ovarian tissue over research use. [Citation needed]

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Healthy premenopausal patients undergoing oophorectomy

        Ovarian tissue can be preserved for future use while allowing for research.

        Clinical Best Practices

        • Obtain IRB-approved protocols for tissue collection.
        • Ensure clear communication and consent regarding tissue use. [Citation needed]
        • Utilize systematic approaches for tissue collection to enhance research quality.

        Related Resources & Content

        Original Source(s)

        Advancing human ovarian biology in tandem with clinical care: considerations for collecting ovarian tissue for research after oophorectomy for tissue cryopreservation

        • by Margaret A. Brunette, Karen Burns, Holly Hoefgen, Shuo Xiao, Francesca E. Duncan, Monica M. Laronda, Ariella Shikanov, Mary Zelinski, Veronica Gomez-Lobo

        • June 3, 2026

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