The Association Between Physical Activity and the Incidence of Cataract and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis of Cohort Studies - Scorecard - MDSpire
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The Association Between Physical Activity and the Incidence of Cataract and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis of Cohort Studies

  • By

  • Dagfinn Aune

  • Ahmad Jayedi

  • Asma Kazemi

  • Sepideh Soltani

  • Fatemeh Rezaei

  • Michael F. Leitzmann

  • March 11, 2026

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Clinical Scorecard: The Association Between Physical Activity and the Incidence of Cataract and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis of Cohort Studies

At a Glance

CategoryDetail
Condition
Key MechanismsPhysical activity may influence metabolic risk factors associated with cataract and age-related macular degeneration, such as obesity and diabetes.
Target Population
Care Setting

Key Highlights

  • Cataract is the leading cause of blindness globally, while age-related macular degeneration is the third.
  • Mixed results observed in studies regarding the association between physical activity and cataract risk.
  • Some studies suggest inverse associations between physical activity and age-related macular degeneration risk.
  • Major risk factors for both conditions include diabetes, hypertension, and higher BMI.
  • Systematic review aimed to clarify the relationship between physical activity and these eye conditions, with a focus on specific studies.

Guideline-Based Recommendations

Diagnosis

    Management

    • Encourage specific types of physical activity, such as aerobic exercises and strength training, as part of lifestyle modification for at-risk populations.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Physical activity may help mitigate risks associated with metabolic factors; consider personalized activity plans.

        Clinical Best Practices

        • Promote regular physical activity tailored to individual capabilities to reduce the risk of cataract and age-related macular degeneration.
        • Implement comprehensive assessments of patient lifestyle and risk factors, including specific recommendations for physical activity.

        Related Resources & Content

        Original Source(s)

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