Survival Duration and Influencing Factors in Cervical Cancer Patients in Tigray, Ethiopia: A Retrospective Analysis
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By
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Gerezgiher Buruh Abera
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Mussie Alemayehu
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Demisew Amenu Sori
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Rahma Ali
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Nega Jibat
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Wondimagegn Adissu
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Haftamu Hailekiros
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Endashaw Nadew
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Ashenafi Alemu
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Alemseged Abdissa
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Nigisti Mulholland
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Gelila K Goba
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Eva J Kantelhardt
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Kim Mulholland
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Prisha Balgovind
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Gerald L. Murray
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Suzanne M. Garland
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March 2, 2026
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Clinical Scorecard: Survival Duration and Influencing Factors in Cervical Cancer Patients in Tigray, Ethiopia: A Retrospective Analysis
At a Glance
| Category | Detail |
|---|
| Condition | Cervical Cancer |
| Key Mechanisms | Persistent infection with high-risk types of human papillomavirus (HPV), primarily HPV-16 and HPV-18. |
| Target Population | Women diagnosed with cervical cancer in Tigray, Ethiopia. |
| Care Setting | Healthcare facilities in Tigray, including specialized hospitals and health centers. |
Key Highlights
- Cervical cancer is the second leading cause of cancer mortality among women in Ethiopia.
- Less than 20% of women survive beyond five years due to late diagnosis and inadequate access to care.
- The armed conflict in Tigray has severely disrupted health services and access to cancer treatment.
- Geographic remoteness and financial constraints limit healthcare access for women.
- Comorbidities such as HIV and malnutrition exacerbate disease progression and mortality.
Guideline-Based Recommendations
Diagnosis
- Implement widespread cervical cancer screening and diagnostic services.
- Utilize pathology services for confirming precancerous cervical lesions.
Management
- Ensure timely treatment options are available for diagnosed patients.
- Address systemic challenges including shortages of trained oncologists and treatment supplies.
Monitoring & Follow-up
- Conduct localized research to understand survival outcomes and prognostic factors.
Risks
- Late-stage diagnosis significantly reduces survival chances.
- Social stigma and lack of awareness delay seeking medical care.
Patient & Prescribing Data
Women diagnosed with cervical cancer in Tigray, particularly in the context of conflict and healthcare disruption.
Access to specialized care and timely treatment is critical for improving survival rates.
Clinical Best Practices
- Promote HPV vaccination and regular cervical screening to reduce incidence.
- Develop crisis-informed interventions to address healthcare disruptions.
References
