Health-related quality of life and tobacco and alcohol consumption in Leber hereditary optic neuropathy in Sweden - Scorecard - MDSpire

Health-related quality of life and tobacco and alcohol consumption in Leber hereditary optic neuropathy in Sweden

  • By

  • Johan Hedström

  • Maria Nilsson

  • Martin Engvall

  • Pete A. Williams

  • Abinaya Priya Venkataraman

  • June 15, 2026

  • 0 min

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Clinical Scorecard: Quality of Life, Tobacco, and Alcohol Use in Individuals with Leber Hereditary Optic Neuropathy in Sweden

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationIndividuals with LHON, asymptomatic carriers, healthy controls, and individuals with other eye diseases in Sweden.
Care Setting

Key Highlights

  • HRQoL similar among LHON cohort compared to healthy controls, but specify the statistical significance.

Guideline-Based Recommendations

Diagnosis

    Management

    • Monitor visual function, provide supportive care for visual impairment, and offer genetic counseling for carriers.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Focus on lifestyle modifications to reduce smoking and alcohol consumption; consider pharmacological interventions if necessary.

        Clinical Best Practices

        • Encourage awareness of risk factors among asymptomatic carriers.
        • Utilize validated HRQoL questionnaires for assessment.
        • Implement regular follow-up for monitoring visual health and substance use.
        • Incorporate multidisciplinary approaches for managing visual impairment.

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        Original Source(s)

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