Clinical Scorecard: Association of Hemoglobin-Albumin-Lymphocyte-Platelet Score with Early Neurological Decline in Acute Ischemic Stroke: A Retrospective Cohort Analysis from a Single Center

At a Glance

Key Highlights

• 186 out of 595 patients (31.3%) developed early neurological deterioration (END).
• Lower HALP scores were associated with a higher risk of END.
• Independent determinants for END included large artery atherosclerosis subtype and elevated baseline NIHSS score.
• A nomogram incorporating HALP score, LAA subtype, and baseline NIHSS score demonstrated moderate discrimination for predicting END.

Guideline-Based Recommendations

Diagnosis

• Use clinical criteria for diagnosing acute ischemic stroke as per Chinese Stroke Association guidelines.

Management

• Implement guideline-based stroke care for vascular risk factor control.

Monitoring & Follow-up

• Monitor HALP scores and NIHSS scores for risk stratification of END.

Risks

• Consider factors such as malnutrition, elevated NIHSS scores, and LAA subtype as risks for END.

Patient & Prescribing Data

Patients with acute ischemic stroke receiving thrombolytic or conservative treatment.

Guideline-based management including statins for eligible patients.

Clinical Best Practices

• Utilize the HALP score for comprehensive risk assessment in acute ischemic stroke patients.
• Incorporate a nomogram for predicting early neurological deterioration.

Related Resources & Content

• Chinese Stroke Association guidelines