Physicians’ acceptance of large language model–based clinical decision support tools in gynecologic oncology: a technology acceptance model study - Scorecard - MDSpire

Physicians’ acceptance of large language model–based clinical decision support tools in gynecologic oncology: a technology acceptance model study

  • By

  • Jan Lennart Stalp

  • Juliane Alexandra Schneider

  • Anna Krause

  • Lena Steinkasserer

  • Jens Hachenberg

  • Agnieszka Denecke

  • Peter Hillemanns

  • Dominik Wolff

  • July 14, 2026

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Clinical Scorecard: Acceptance of Clinical Decision Support Tools Utilizing Large Language Models by Physicians in Gynecologic Oncology: A Study Based on Technology Acceptance Model

At a Glance

CategoryDetail
ConditionGynecologic Oncology
Key MechanismsLarge language model-based clinical decision support systems (LLM-CDSS) assist in therapy planning by synthesizing patient-specific information with up-to-date evidence and guidelines.
Target PopulationPhysicians in gynecologic oncology
Care SettingTertiary hospital

Key Highlights

  • Physicians showed a generally positive but cautious attitude towards LLM-CDSS.
  • Acceptance of LLM-CDSS depends on transparency, clinical validation, and physician oversight.
  • Concerns about patient trust and clinical autonomy were noted among participants.
  • No significant factors were identified influencing willingness to use LLM-CDSS.
  • The study emphasizes the need for expert oversight and prospective clinical validation.

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

        Risks

        • Concerns regarding impaired trust, transparency, and data protection in oncology.

        Patient & Prescribing Data

        Not specified in the study.

        LLM-CDSS could potentially improve consistency of care and reduce cognitive burdens.

        Clinical Best Practices

        • LLM-CDSS should support rather than replace physician decision-making.
        • Transparency and clinical validation are crucial for acceptance.

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