Diagnosis and treatment strategies for airway involvement in relapsing polychondritis: a comprehensive review
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By
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Pengcheng Zhou
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Wei Yu
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Jianli Ma
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Wensheng Zhang
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Yan Dong
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Chengshi He
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June 4, 2026
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Clinical Scorecard: Approaches to Diagnosing and Managing Airway Complications in Relapsing Polychondritis: An In-Depth Review
At a Glance
| Category | Detail |
|---|
| Condition | |
| Key Mechanisms | Inflammatory damage to airway cartilage. |
| Target Population | |
| Care Setting | Multidisciplinary clinical settings with access to imaging and endoscopic evaluations. |
Key Highlights
- Airway involvement occurs in approximately 50% of RP patients and is a major cause of mortality.
- Imaging techniques like CT and bronchoscopy have high diagnostic value for airway lesions.
Guideline-Based Recommendations
Diagnosis
- Utilize imaging (CT, PET/CT) and endoscopic examinations (bronchoscopy) for assessment.
Management
- Employ glucocorticoids and immunosuppressants for inflammatory control.
Monitoring & Follow-up
- Regular imaging and endoscopic evaluations to assess airway condition.
Risks
- High operational risks associated with endoscopic examinations in patients with impaired lung function.
Patient & Prescribing Data
Patients with relapsing polychondritis experiencing airway complications.
Combination of traditional immunosuppressants and newer biologics may improve outcomes.
Clinical Best Practices
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