Worldwide prevalence of Toxocara infection among children: A systematic review and meta-analysis of an overlooked parasitic risk - Scorecard - MDSpire

Worldwide prevalence of Toxocara infection among children: A systematic review and meta-analysis of an overlooked parasitic risk

  • By

  • Nassim Rezapour

  • Helia Ghaffari Hamedani

  • Mahdi Sepidarkish

  • Nazanin Kianifard

  • Morteza Sheikhi Nooshabadi

  • Hamid Parsa

  • Kimia Bagheri

  • Maryam Ebrahimi

  • Mohsen Mohammadi

  • Neda Ahmadzadeh Tori

  • Seema Advani

  • Ashkan Garshasbi

  • Diba Mohammadi

  • Fatemeh Zahra Asadpour

  • Ali Rostami

  • December 29, 2025

  • 0 min

Share

Clinical Scorecard: Worldwide prevalence of Toxocara infection among children: A systematic review and meta-analysis of an overlooked parasitic risk

At a Glance

CategoryDetail
ConditionToxocara infection (toxocariasis)
Key MechanismsTransmission through ingestion of embryonated eggs from contaminated environments or close contact with infected pets.
Target PopulationChildren, particularly those aged ≤ 19 years.
Care SettingCommunity, schools, or healthcare facilities.

Key Highlights

  • Toxocara infection is a significant public health concern, especially among children.
  • Children's behaviors increase their susceptibility to Toxocara infection.
  • Clinical manifestations can range from asymptomatic to severe, including neurological and allergic conditions.
  • Serological tests are crucial for diagnosis but face accessibility challenges in resource-poor regions.
  • The study aims to quantify pediatric seroprevalence and identify priority populations for intervention.

Guideline-Based Recommendations

Diagnosis

  • Use serological tests, particularly ELISAs, for detecting Toxocara infection.

Management

  • Implement evidence-based prevention strategies targeting high-risk populations.

Monitoring & Follow-up

  • Establish robust, age-stratified estimates of T-seroprevalence.

Risks

  • Consider geophagy and poor hygiene practices as significant risk factors.

Patient & Prescribing Data

Children from various ages, ethnicities, and socioeconomic backgrounds.

Focus on prevention and early detection due to the range of clinical manifestations.

Clinical Best Practices

  • Encourage improved hygiene practices among children.
  • Educate families about the risks of Toxocara infection.
  • Promote regular health checkups in communities with high prevalence.

References

Original Source(s)

Related Content