The correlation between fine needle aspiration diagnosis and postoperative histopathological results of pediatric thyroid nodules based on the Bethesda system - Scorecard - MDSpire
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The correlation between fine needle aspiration diagnosis and postoperative histopathological results of pediatric thyroid nodules based on the Bethesda system
Clinical Scorecard: The Relationship Between Fine Needle Aspiration Outcomes and Surgical Histopathology in Pediatric Thyroid Nodules According to the Bethesda Classification
At a Glance
Category
Detail
Condition
Pediatric Thyroid Nodules
Key Mechanisms
Fine needle aspiration (FNA) and Bethesda System for Reporting Thyroid Cytopathology (TBSRTC)
Target Population
Pediatric patients aged ≤ 18 years
Care Setting
First Affiliated Hospital of Zhengzhou University
Key Highlights
Higher malignancy rates in pediatric thyroid nodules compared to adults.
Overall risk of malignancy ranged from 32.76% to 92.68% based on Bethesda categories.
Papillary thyroid carcinoma was the predominant histological type (88.62%).
Bethesda system demonstrated high sensitivity (98.58%) and specificity (100%).
BRAF V600E mutation detected in 51.53% of malignancies.
Guideline-Based Recommendations
Diagnosis
Utilize the Bethesda System for Reporting Thyroid Cytopathology for FNA results.
Management
Consider surgical intervention for indeterminate and malignant FNA results.
Monitoring & Follow-up
Regular surveillance for nodules with significant changes in size or characteristics.
Risks
Increased risk of malignancy in pediatric patients with indeterminate FNA results.
Patient & Prescribing Data
Pediatric patients with thyroid nodules undergoing FNA.
BRAF V600E testing is valuable for preoperative risk stratification.
Clinical Best Practices
Adhere to C-TIRADS guidelines for indications of FNA.
Ensure careful interpretation of FNA results considering age-related differences.
