Maternal and Peri/Neonatal Mortality and Morbidity in Midwife-Assisted Low-Risk Birth Outside Hospital Compared to Obstetric Team-Assisted Low-Risk Hospital Birth: A Systematic Review and Meta-Analysis - Scorecard - MDSpire

Comparative Analysis of Maternal and Perinatal Mortality and Morbidity in Low-Risk Births Assisted by Midwives Outside of Hospitals Versus Those Managed by Obstetric Teams in Hospital Settings: A Systematic Review and Meta-Analysis

  • By

  • Carolina Herding

  • Ulla-Britt Wennerholm

  • Anders Elfvin

  • Sara Holm

  • Karolina Linden

  • Jahangir Khan

  • Max Petzold

  • Christina Bergh

  • Petteri Sjögren

  • Ida Stadig

  • Ann Liljegren

  • Ylva Carlsson

  • Verena Sengpiel

  • July 20, 2026

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Clinical Scorecard: Comparative Analysis of Maternal and Perinatal Mortality and Morbidity in Low-Risk Births Assisted by Midwives Outside of Hospitals Versus Those Managed by Obstetric Teams in Hospital Settings: A Systematic Review and Meta-Analysis

At a Glance

CategoryDetail
ConditionLow-Risk Births
Key MechanismsComparison of maternal and neonatal outcomes between midwife-assisted out-of-hospital births and obstetric team-assisted hospital births.
Target PopulationWomen with expected low-risk births in high-income countries.
Care SettingOut-of-hospital settings (home births and freestanding midwifery units) versus hospital obstetric units.

Key Highlights

  • Planned out-of-hospital births may offer fewer obstetric interventions.
  • Higher maternal satisfaction reported in out-of-hospital settings.
  • Conflicting evidence on neonatal outcomes in planned out-of-hospital births.
  • Variability in planned out-of-hospital birth rates across high-income countries.
  • Need for rigorous evidence synthesis to clarify risks and benefits.

Guideline-Based Recommendations

Diagnosis

  • Expected low-risk births defined as singletons, cephalic position, spontaneous onset of labour, normal blood pressure, no previous caesarean section, and full term.

Management

  • Consideration of maternal and neonatal risks in the choice of birth setting.

Monitoring & Follow-up

  • Ongoing assessment of maternal and neonatal outcomes in different birth settings.

Risks

  • Potential for higher peri/neonatal mortality in planned out-of-hospital births, especially among nulliparous women.

Patient & Prescribing Data

Women with expected low-risk births.

Out-of-hospital births may be a viable option but require careful consideration of individual circumstances.

Clinical Best Practices

  • Integration of midwifery education in accordance with International Confederation of Midwives (ICM) criteria.
  • Use of systematic reviews and meta-analyses to inform clinical practice.

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