Type I to type II Boston keratoprosthesis exchange: a report of two patients
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By
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Lourdes Salgueiro Tielas
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Michael Bednar
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Ramez Haddadin
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James Chodosh
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Thomas H. Dohlman
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June 17, 2026
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Clinical Scorecard: Exchange of Type I to Type II Boston Keratoprosthesis: A Case Study of Two Patients
At a Glance
| Category | Detail |
| Condition | |
| Key Mechanisms | Type I BKPro for multiple failed grafts; Type II BKPro for severe ocular surface disease. |
| Target Population | |
| Care Setting | |
Key Highlights
- Type I BKPro is first-line for patients with multiple failed corneal grafts.
- Type II BKPro is designed for patients with severe ocular surface disease.
- Long-term complications of Type I BKPro may necessitate transition to Type II.
- Two case studies demonstrate the feasibility of BKPro exchange.
Guideline-Based Recommendations
Diagnosis
- Evaluate patients with severe corneal blindness for BKPro candidacy.
Management
- Consider Type I BKPro for patients with multiple failed grafts.
- Use Type II BKPro for patients with severe ocular surface disease.
Monitoring & Follow-up
- Regular follow-up for complications such as corneal melting and device extrusion.
Risks
- Potential for infection, device extrusion, and corneal melting.
Patient & Prescribing Data
Patients with severe ocular surface disease and history of failed corneal grafts.
Immunosuppression may be necessary postoperatively; monitor for complications.
Clinical Best Practices
- Initiate immunosuppressive therapy pre- and post-operatively as indicated.
- Perform regular assessments of visual acuity and intraocular pressure.
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