Acute liver failure and secondary TMA-like phenomenon following SARS-CoV-2 and Mycoplasma pneumoniae co-detection in a child: a case report - Scorecard - MDSpire
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Acute liver failure and secondary TMA-like phenomenon following SARS-CoV-2 and Mycoplasma pneumoniae co-detection in a child: a case report
Clinical Scorecard: Acute liver failure and a TMA-like condition in a child with concurrent SARS-CoV-2 and Mycoplasma pneumoniae infection: a case study
At a Glance
Category
Detail
Condition
Key Mechanisms
Co-detection of SARS-CoV-2 and Mycoplasma pneumoniae leading to severe hyperinflammation and organ dysfunction
Target Population
Care Setting
Key Highlights
20-month-old girl presented with sepsis and acute liver failure
Severe hyperinflammation indicated by elevated ferritin and IL-6 levels
Development of secondary TMA-like phenomenon characterized by thrombocytopenia and acute kidney injury
Guideline-Based Recommendations
Diagnosis
Comprehensive etiological workup including microbiological testing for SARS-CoV-2 and M. pneumoniae
Management
Aggressive supportive care including fluid resuscitation and glucocorticoids
Monitoring & Follow-up
Monitoring for signs of secondary TMA-like phenomenon in patients with severe hyperinflammation
Risks
Potential for acute liver failure and secondary thrombotic microangiopathy in co-detected infections
Patient & Prescribing Data
Previously healthy children with concurrent SARS-CoV-2 and M. pneumoniae infections
