Subtypes of Symptoms and Endoscopic Findings in Gastro-oesophageal Reflux Disease: A Retrospective Cross-Sectional Analysis from Southwestern Nigeria - Scorecard - MDSpire

Subtypes of Symptoms and Endoscopic Findings in Gastro-oesophageal Reflux Disease: A Retrospective Cross-Sectional Analysis from Southwestern Nigeria

  • By

  • E Odeghe

  • A Itam-Eyo

  • A Oluyemi

  • O Owoseni

  • A Nnadi

  • J Uchechukwu

  • O Onodingene

  • S Tamunodukobipi

  • O Adeniyi

  • M Lawal

  • G Oyeleke

  • October 24, 2025

  • 0 min

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Clinical Scorecard: Subtypes of Symptoms and Endoscopic Findings in Gastro-oesophageal Reflux Disease: A Retrospective Cross-Sectional Analysis from Southwestern Nigeria

At a Glance

CategoryDetail
ConditionGastro-oesophageal reflux disease (GORD)
Key MechanismsRetrograde flow of gastric contents into the oesophagus causing symptoms and complications.
Target PopulationAdults (≥ 18 years) with GORD symptoms.
Care SettingEndoscopy suites of two centres in southwest Nigeria.

Key Highlights

  • GORD prevalence in Nigeria ranges from 7.6% to 33%.
  • 74.5% of patients diagnosed with GORD have non-erosive reflux disease (NERD).
  • Typical symptoms include heartburn and regurgitation; atypical symptoms include chronic cough and asthma.
  • Endoscopic findings may show mucosal injury or be non-erosive.
  • Obesity and dietary factors are linked to GORD symptoms.

Guideline-Based Recommendations

Diagnosis

  • Diagnosis is clinical and based on symptom presentation.
  • Endoscopy is used to identify mucosal injury but is not required for diagnosis.

Management

  • Weight loss and dietary modifications are recommended.
  • Mild physical activity may alleviate symptoms.

Monitoring & Follow-up

  • Regular assessment of symptom severity and endoscopic findings.

Risks

  • Increased mortality associated with GORD, particularly in those without oesophagitis.

Patient & Prescribing Data

Adults with GORD symptoms presenting for upper gastrointestinal endoscopy.

Management should focus on lifestyle modifications and symptom control.

Clinical Best Practices

  • Identify and address modifiable risk factors for GORD.
  • Consider both oesophageal and extra-oesophageal symptoms in management.
  • Utilize endoscopy judiciously to assess for mucosal injury.

References

Original Source(s)

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