Prevalence and risk factors of hyperuricemia and gout in patients with type 2 diabetes mellitus: a systematic review and meta-analysis - Scorecard - MDSpire
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Prevalence and risk factors of hyperuricemia and gout in patients with type 2 diabetes mellitus: a systematic review and meta-analysis
Clinical Scorecard: Global Prevalence and Associated Risk Factors of Hyperuricemia and Gout in Individuals with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
At a Glance
Category
Detail
Condition
Hyperuricemia and Gout in Type 2 Diabetes Mellitus
Key Mechanisms
Insulin resistance, oxidative stress, activation of the renin-angiotensin-aldosterone system
Target Population
Patients with Type 2 Diabetes Mellitus
Care Setting
Clinical management of Type 2 Diabetes Mellitus
Key Highlights
Pooled prevalence of hyperuricemia in T2DM is 22.0%
Pooled prevalence of gout in T2DM is 6.0%
Impaired renal function, obesity, dyslipidemia, hypertension, metabolic syndrome, and alcohol consumption are key risk factors for hyperuricemia
Male sex is a significant risk factor for gout
Routine serum uric acid monitoring is recommended for high-risk individuals
Guideline-Based Recommendations
Diagnosis
Routine screening for hyperuricemia and gout in T2DM patients
Management
Incorporate early screening for high-risk individuals into clinical management
Monitoring & Follow-up
Regular serum uric acid level monitoring
Risks
Increased risk of vascular complications and kidney damage in patients with T2DM and hyperuricemia/gout
Patient & Prescribing Data
Adults aged ≥18 years with Type 2 Diabetes Mellitus
Focus on managing risk factors such as renal function, obesity, and dyslipidemia
Clinical Best Practices
Utilize a systematic approach for screening and managing hyperuricemia and gout in T2DM patients
Assess geographic variations in prevalence for targeted interventions
Educate patients on lifestyle modifications to reduce risk factors
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