Primary headache disorders susceptibility is associated with fasting-related headache: evidence from a multinational study across 14 countries - Scorecard - MDSpire

Primary headache disorders susceptibility is associated with fasting-related headache: evidence from a multinational study across 14 countries

  • By

  • M. Ceren Akgor

  • K. Saghır

  • A. İ. Can

  • F. G. Sahbaz

  • E. U. Özcelik

  • A. C. Atalar

  • N. Ergin

  • M. O. Orun

  • A. A. Madani

  • E. A. A. Ibrahim

  • M. Togha

  • S. Amirguliyev

  • Y. Alabwah

  • J. A. Hashel

  • I. M. Dardar

  • R. E. Sahli

  • S. B. Sassi

  • M. Nada

  • N. Shalaby

  • Y. Dehal

  • Y. Naji

  • M. Amine

  • K. Alfred

  • R. Karacı

  • E. Yanık

  • G. Gürsoy

  • H. T. Celik

  • S. Tasdelen

  • E. Ekizoğlu

  • E. K. Orhan

  • D. Agırcan

  • H. Genc

  • T. Gesoglu Demir

  • F. M. Domac

  • N. Köse

  • N. Tepe

  • S. Öztürk

  • E. K. Cengiz

  • K. Erdogan

  • İ. Yıldırım

  • B. R. Hasırcı Bayır

  • E. A. Demirel

  • R. Ghouri

  • B. Tasdelen

  • H. Bolay

  • A. Ozge

  • N. Kissani

  • June 25, 2026

  • 0 min

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Clinical Scorecard: Association Between Susceptibility to Primary Headache Disorders and Headaches During Fasting: Findings from a Multinational Study Involving 14 Countries

At a Glance

CategoryDetail
ConditionFasting-related headache
Key MechanismsInfluenced by pre-existing primary headache disorders and lifestyle-related factors
Target PopulationAdults (18–65 years) observing Ramadan fasting
Care SettingMultinational cross-sectional survey

Key Highlights

  • Headache attacks primarily occur in the afternoon/pre-iftar period.
  • 54.6% of participants reported improvement after iftar.
  • Pre-existing primary headache disorders, especially migraine, are strongly associated with headache occurrence during fasting.

Guideline-Based Recommendations

Diagnosis

  • Headache attributed to fasting is classified as a secondary headache attributed to a disorder of homeostasis.

Management

  • Consider individual headache history alongside fasting-related exposures when assessing vulnerability.

Monitoring & Follow-up

  • Monitor headache characteristics such as intensity, duration, and associated symptoms during fasting.

Risks

  • Individuals with a history of primary headache disorders may be at higher risk for fasting-related headaches.

Patient & Prescribing Data

Adults observing Ramadan fasting with a history of primary headache disorders.

Headache relief is often experienced after breaking the fast.

Clinical Best Practices

  • Utilize a structured questionnaire aligned with ICHD-3 for headache classification.
  • Assess lifestyle factors and headache history in patients experiencing fasting-related headaches.

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