Venous Thromboembolism and Secondary Outcomes of Bleeding and Mortality in Patients with Gliomas: A Multicenter Cohort Study - Scorecard - MDSpire

Venous Thromboembolism and Secondary Outcomes of Bleeding and Mortality in Patients with Gliomas: A Multicenter Cohort Study

  • By

  • Veiga, Viviane Cordeiro

  • Yamada, Camilla A. F.

  • Clara, Carlos Afonso

  • Santos, Jéssica Carolina Andrade

  • Milano, Breno Gray

  • Matias, Danielli Almeida

  • Melo, Pedro Hortêncio Saboia da Escossia

  • Batistella, Gabriel Novaes de Rezende

  • Cavalcanti, Alexandre Biasi

  • Viola, Fabiana Spillari

  • Levy, Ana Carolina

  • Santos, Silvana Soares

  • Fittipaldi, Carolina

  • Pinto, Mauro Bráulio da Rosa

  • Oliveira, Daniela Galvão Barros

  • Vieira, Thiago Santos

  • Moraes, Flavia Regina

  • Ostolin, Thatiane Lopes Valentim Di Paschoaele

  • Belucci, Talita Rantin

  • Chaddad-Neto, Feres

  • Baeta, Alex Machado

  • Neville, Iuri Santana

  • Peres, Stela Verzinhasse

  • April 30, 2026

  • 0 min

Share

Clinical Scorecard: Incidence of Venous Thromboembolism and Associated Risks of Hemorrhage and Mortality in Glioma Patients: A Multicenter Retrospective Analysis

At a Glance

CategoryDetail
ConditionVenous Thromboembolism (VTE) in glioma patients
Key MechanismsIncreased risk associated with prior VTE, corticosteroid use, chronic kidney failure, and diabetes mellitus.
Target PopulationAdults with histologically confirmed primary gliomas
Care SettingMulticenter study across nine Brazilian centers

Key Highlights

  • 12-month cumulative incidence of VTE: 11.8%
  • 12-month cumulative incidence of bleeding: 4.7%
  • Cumulative mortality incidence: 26.2%
  • Prior VTE and corticosteroid use significantly increase VTE risk.
  • Mortality risk associated with gliomas NOS and GBM.

Guideline-Based Recommendations

Diagnosis

  • Assess VTE risk factors in glioma patients.

Management

  • Consider thromboprophylaxis in high-risk patients.

Monitoring & Follow-up

  • Monitor for signs of VTE and bleeding postoperatively.

Risks

  • Higher mortality associated with prolonged hospitalization and postoperative bleeding.

Patient & Prescribing Data

334 adults with primary gliomas

Corticosteroid use and prior VTE are critical considerations in treatment planning.

Clinical Best Practices

  • Individualized risk stratification for VTE and mortality.
  • Utilize specialized cancer centers for treatment.

Related Resources & Content

Original Source(s)

Venous Thromboembolism and Secondary Outcomes of Bleeding and Mortality in Patients with Gliomas: A Multicenter Cohort Study

  • by Veiga, Viviane Cordeiro, Yamada, Camilla A. F., Clara, Carlos Afonso, Santos, Jéssica Carolina Andrade, Milano, Breno Gray, Matias, Danielli Almeida, Melo, Pedro Hortêncio Saboia da Escossia, Batistella, Gabriel Novaes de Rezende, Cavalcanti, Alexandre Biasi, Viola, Fabiana Spillari, Levy, Ana Carolina, Santos, Silvana Soares, Fittipaldi, Carolina , Pinto, Mauro Bráulio da Rosa, Oliveira, Daniela Galvão Barros, Vieira, Thiago Santos, Moraes, Flavia Regina, Ostolin, Thatiane Lopes Valentim Di Paschoaele, Belucci, Talita Rantin, Chaddad-Neto, Feres , Baeta, Alex Machado, Neville, Iuri Santana, Peres, Stela Verzinhasse

  • April 30, 2026

Related Content

Papillary thyroid carcinoma with brain and lung metastases: a case report

Dana Farber/Boston Children’s Researchers Uncover Distinct Tumor “neighborhoods” with Each Cell Subtype Playing a Specific Role, in Aggressive Childhood Brain Cancer

Their detailed blueprint of tumor cell diversity could guide more precise, targeted treatments for supratentorial ependymomas 

  • by

  • March 12, 2026

  • 3 min
High-grade astrocytoma with piloid features: a case report of comprehensive management