Combination of Narrow-Margin Hepatectomy and External Beam Radiotherapy for Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis - Scorecard - MDSpire

Combination of Narrow-Margin Hepatectomy and External Beam Radiotherapy for Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis

  • By

  • Tingli Lu

  • Yaqiong Wang

  • Boyu Chen

  • Weida Meng

  • Hai Huang

  • December 27, 2025

  • 0 min

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Clinical Scorecard: Combination of Narrow-Margin Hepatectomy and External Beam Radiotherapy for Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis

At a Glance

CategoryDetail
Condition
Key MechanismsNarrow-margin hepatectomy combined with external beam radiotherapy (EBRT) may reduce local recurrence and improve prognosis, but requires further validation.
Target Population
Care Setting

Key Highlights

  • highlight_4

Guideline-Based Recommendations

Diagnosis

    Management

    • Consider narrow-margin hepatectomy for patients with central HCC, supported by recent studies.
    • Evaluate the potential benefits of adjuvant EBRT to reduce recurrence, referencing current clinical trials.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Patients with HCC undergoing narrow-margin hepatectomy.

        Adjuvant treatments like EBRT may improve outcomes but require further evaluation.

        Clinical Best Practices

        • best_practice_1

        References

        Original Source(s)

        Combination of Narrow-Margin Hepatectomy and External Beam Radiotherapy for Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis

        • by Tingli Lu, Yaqiong Wang, Boyu Chen, Weida Meng, Hai Huang

        • December 27, 2025

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