Epidemiology of respiratory syncytial virus in a German hospital before, during and after the COVID-19 pandemic – a real world monocentric analysis over ten years - Scorecard - MDSpire

Epidemiology of respiratory syncytial virus in a German hospital before, during and after the COVID-19 pandemic – a real world monocentric analysis over ten years

  • By

  • Svenja Loerch

  • Frank Erdnüß

  • Beate Frerich

  • Thorsten Reineke

  • Wolfgang Kamin

  • May 4, 2026

  • 0 min

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Clinical Scorecard: Analysis of Respiratory Syncytial Virus Epidemiology in a German Pediatric Hospital Before, During, and After the COVID-19 Pandemic: A Decadal Monocentric Study

At a Glance

CategoryDetail
ConditionRespiratory Syncytial Virus (RSV) Infection
Key MechanismsSeasonal patterns influenced by COVID-19 pandemic interventions
Target PopulationPediatric patients, primarily infants under 2 years
Care SettingPediatric hospital

Key Highlights

  • RSV seasons shifted significantly during and after the COVID-19 pandemic.
  • Increased hospitalization rates and severity observed in the post-pandemic season.
  • Bacterial superinfection and antibiotic treatment were more frequent post-pandemic.

Guideline-Based Recommendations

Diagnosis

  • Laboratory confirmation of RSV infection in patients with bronchitis, bronchiolitis, or pneumonia.

Management

  • Consideration of prophylactic interventions such as nirsevimab and RSVpreF vaccine.

Monitoring & Follow-up

  • Ongoing surveillance of RSV patterns to inform healthcare resource allocation.

Risks

  • Increased risk of severe disease in infants and potential for bacterial superinfection.

Patient & Prescribing Data

Children under 12 years, primarily those under 2 years.

Nirsevimab shows 93% effectiveness against RSV-associated hospitalization.

Clinical Best Practices

  • Target prophylactic measures towards high-risk groups such as infants and pregnant women.
  • Timely intervention based on seasonal RSV patterns.

References

Original Source(s)

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