Histological features include papillary and ductal structures with fibrovascular axes; immunohistochemical markers include TTF-1 and CK positivity, TG negativity, and low Ki-67 index.
Target Population
Patients with nasopharyngeal tumors, particularly those presenting with nasal obstruction and related symptoms.
Care Setting
Clinical and pathological assessment in a hospital setting.
Key Highlights
TL-LGNPPA is a rare tumor with indolent behavior and good prognosis.
Common symptoms include nasal obstruction, nasal bleeding, and rhinorrhea.
Histological examination reveals papillary architecture and mild to moderate atypia.
Immunohistochemical analysis shows TTF-1 and CK expression, with Ki-67 index usually ≤10%.
Accurate diagnosis requires comprehensive histological and immunohistochemical evaluation.
